Trying to pick the best biotech stocks for 2017 — defined as those with the best returns — is a bit of a crapshoot. The biotech stocks that ultimately produce the best returns are likely to be the ones that investors had little confidence in. You can certainly find winners among the biotech stocks that others have left for dead, but you’ll have to avoid the companies that deserve to be at the bottom of the totem pole, which can be difficult.